This content is for educational purposes only. Not medical advice. Always consult a licensed healthcare professional before using any peptides.

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MetabolicModerate RiskNot FDA-approved. Phase II/III clinical trials ongoing.

SS-31 (Elamipretide)

The Mitochondrial Healer

SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that binds to cardiolipin in the inner mitochondrial membrane, restoring electron transport chain function and reducing reactive oxygen species. Currently in clinical trials for Barth syndrome, heart failure, and mitochondrial myopathy, it represents a first-in-class approach to directly repairing mitochondrial dysfunction.

If You Take This

  • Directly targets and repairs mitochondrial membranes
  • Reduces mitochondrial reactive oxygen species
  • Restores electron transport chain efficiency
  • In clinical trials for heart failure and Barth syndrome
  • Improves cellular energy production (ATP)
  • Protects against age-related mitochondrial decline

Protocol

Dosing
0.25mg/kg subcutaneous daily (clinical trial dosing). For a 80kg individual: ~20mg daily. Research protocols vary — start conservatively.
Cycle Length
4-8 week cycles. Clinical trials have tested up to 28 weeks of continuous dosing. Cycle based on research protocol and practitioner guidance.
Half-Life
4 hours
Best Time
Morning
Method
Subcutaneous injection (clinical trials also use IV infusion)

Stacks Well With

Humanin (mitochondrial synergy)MOTS-C (metabolic complement)CoQ10 supplementation

Avoid With

Limited interaction dataMonitor with cardiac medications

Side Effects

  • Injection site reactions
  • Headache
  • Generally well tolerated in clinical trials
  • Long-term safety profile being established
  • Mild fatigue during initial adaptation

Where to Buy

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We track prices across 5+ verified vendors so you don't have to. Every vendor is vetted for purity testing, third-party COAs, and shipping reliability.

Prices last verified: April 3, 2026

Ascension Peptides

★ 4.7
BEST PRICE
$3.98
Vial
10mg
Purity
99%+
Shipping
2-4 business days
Status
In Stock
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Pinnacle Peptide Labs

★ 4.3
BEST PURITY
$69.99
Vial
10mg
Purity
599%
Shipping
—
Status
In Stock
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For educational and informational purposes only. Not medical advice. Always consult a healthcare provider before starting any peptide protocol.