This content is for educational purposes only. Not medical advice. Always consult a licensed healthcare professional before using any peptides.

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MetabolicModerate RiskNot FDA-approved. Preclinical research compound.

Humanin

The Longevity Guardian

Humanin is a mitochondrial-derived peptide (MDP) encoded in the mitochondrial genome that plays a critical role in cellular stress protection and longevity. Higher circulating humanin levels have been found in centenarian populations, suggesting a direct link to lifespan. It is cytoprotective, insulin-sensitizing, and anti-inflammatory, representing the cutting edge of longevity peptide research.

If You Take This

  • Linked to centenarian populations and longevity
  • Powerful cytoprotective effects against cellular stress
  • Improves insulin sensitivity
  • Reduces systemic inflammation
  • Protects against neurodegenerative processes
  • Supports mitochondrial function and biogenesis

Protocol

Dosing
Research dosing varies: 1-5mg subcutaneous injection. Most protocols use 1-3mg daily. Optimal dosing not yet established in humans.
Cycle Length
Research protocols typically run 4-8 weeks. Long-term data limited. Cycling recommended pending further research.
Half-Life
2-4 hours
Best Time
Morning
Method
Subcutaneous injection

Stacks Well With

SS-31 (mitochondrial synergy)MOTS-C (fellow MDP)NAD+ precursors

Avoid With

Very limited interaction data — use caution with any metabolic medicationsNot combined with other experimental peptides without monitoring

Side Effects

  • Very limited human safety data
  • Injection site irritation
  • Possible immune modulation
  • Theoretical concerns about growth-promoting effects in cancer

Where to Buy

PepStack Price Guarantee

We track prices across 5+ verified vendors so you don't have to. Every vendor is vetted for purity testing, third-party COAs, and shipping reliability.

Prices last verified: April 2, 2026

Core Peptides

★ 4.8
BEST PRICE
$147.00
Vial
10mg
Purity
99%
Shipping
2-3 business days
Status
In Stock
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For educational and informational purposes only. Not medical advice. Always consult a healthcare provider before starting any peptide protocol.