This content is for educational purposes only. Not medical advice. Always consult a licensed healthcare professional before using any peptides.

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Weight LossModerate RiskNot FDA-approved. Preclinical/early research compound.

5-Amino-1MQ

The NNMT Inhibitor

5-Amino-1MQ is a small molecule that inhibits nicotinamide N-methyltransferase (NNMT), an enzyme overexpressed in fat tissue that contributes to obesity and metabolic dysfunction. By blocking NNMT, it boosts NAD+ levels, promotes fat cell shrinkage, and enhances cellular energy metabolism. One of the newer and most promising oral compounds for metabolic optimization.

If You Take This

  • Inhibits NNMT enzyme to reduce fat accumulation
  • Boosts NAD+ levels for cellular energy
  • Promotes shrinkage of fat cells (adipocytes)
  • Enhances metabolic rate without stimulant effects
  • Supports healthy cholesterol levels
  • Oral dosing — no injections required

Protocol

Dosing
50-150mg oral daily, typically split into 1-2 doses. Most common protocol is 100mg once daily with food.
Cycle Length
6-12 weeks. Some run continuous cycles with periodic breaks. Long-term safety data is limited.
Half-Life
12 hours
Best Time
Morning with breakfast
Method
Oral (capsule)

Stacks Well With

Avoid With

No well-documented contraindications yetCaution with other NAD+-boosting supplements at high doses

Side Effects

  • Mild GI discomfort at higher doses
  • Headache during first few days
  • Limited long-term human safety data
  • Possible mild diuretic effect

Where to Buy

PepStack Price Guarantee

We track prices across 5+ verified vendors so you don't have to. Every vendor is vetted for purity testing, third-party COAs, and shipping reliability.

Prices last verified: April 3, 2026

Ascension Peptides

4.7
BEST PRICE
$3.98
Vial
10mg
Purity
99%+
Shipping
2-4 business days
Status
In Stock
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Pinnacle Peptide Labs

4.3
$39.99
Vial
5mg
Purity
99%
Shipping
Status
In Stock
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Limitless Biotech

4.5
BEST PURITY
$209.99
Vial
30ct (50mg)
Purity
99.19%
Shipping
3-5 business days
Status
In Stock
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For educational and informational purposes only. Not medical advice. Always consult a healthcare provider before starting any peptide protocol.